DISEASES

Children are infected with the virus without suffering a serious disease and represent an important source of infection. It has been experimentally proven that young mice respond to lung tissue damage from viral infection through prostaglandins, while adult mice succumb. The angiotensinconverting enzyme (ACE) 2 receptor is particularly abundant on the cells of the lower lung pathways, whose situation explains the high incidence of bronchitis and pneumonia related to the severe infection of COVID-19. A fall in ACE2 activity in the elderly is partly responsible for the decreased ability to reduce the inflammatory response with old age. The reduction of ACE2 receptors in older adults puts them in a position where they are unable to cope with COVID-19. In Italy from the details of the medical records of the current hospitalized as well as those discharged healed and unfortunately the victims do not seem to have any foreigner in the sense of a non-EU citizen.Non-EU citizens are all covered by a tuberculosis vaccine which is part of a coverage protocol provided by the Local Health Unit.It seems that flu vaccination favors coronavirus infection, even greater than 36% as reported by an American military study. Both meningococcal and pneumociccic disease have been associated with the activity of influenza and respiratory syncytial viruses.The Istituto Superiore della Sanità recently stated that few deaths are from coronavirus and instead most put of them from other pathologies (cardiovascular, cancer, diabetes,etc.). This suggests that the overall clinical consequences of COVID-19 could ultimately be similar to that of severe seasonal flu, which has a fatality rate of approximately 0.1%, or pandemic influenza such as that of 1957 or 1968. , rather than those of SARS or MERS, characterized respectively by a fatality of 10% and 36%.