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The effect of Mindfulness-Based Stress Reduction on wound healing: a preliminary study.

Abstract Title: The effect of Mindfulness-Based Stress Reduction on wound healing: a preliminary study. Abstract Source: J Behav Med. 2018 Jun ;41(3):385-397. Epub 2017 Nov 20. PMID: 29159589 Abstract Author(s): Astrid Meesters, Yvo M C In den Bosch-Meevissen, Chantal A H Weijzen, Wim A Buurman, Mario Losen, Jan Schepers, Monique R T M Thissen, Hugo J E M Alberts, Casper G Schalkwijk, Madelon L Peters Article Affiliation: Astrid Meesters Abstract: Psychological factors have been shown to influence the process of wound healing. This study examined the effect of Mindfulness-Based Stress Reduction (MBSR) on the speed of wound healing. The local production of pro-inflammatory cytokines and growth factors was studied as potential underlying mechanism. Forty-nine adults were randomly allocated to a waiting-list control group (n = 26) or an 8-week MBSR group (n = 23). Pre- and post-intervention/waiting period assessment for both groups consisted of questionnaires. Standardized skin wounds were induced on the forearm using a suction blister method. Primary outcomes were skin permeability and reduction in wound size monitored once a day at day 3, 4, 5, 6, 7, and 10 after injury. Secondary outcomes were cytokines and growth factors and were measured in wound exudates obtained at 3, 6, and 22 h after wounding. Although there was no overall condition effect on skin permeability or wound size, post hoc analyses indicated that larger increases in mindfulness were related to greater reductions in skin permeability 3 and 4 days after wound induction. In addition, MBSR was associated with lower levels of interleukin (IL)-8 and placental growth factor in the wound fluid 22 h after wound induction. These outcomes suggest that increasing mindfulness by MBSR might have beneficial effects on early stages of wound healing. Trial Registration NTR3652, http://www.trialregister.nl. Article Published Date : May 31, 2018

Four Weekly Ayahuasca Sessions Lead to Increases in"Acceptance"Capacities: A Comparison Study With a Standard 8-Week Mindfulness Training Program. 📎

Abstract Title: Four Weekly Ayahuasca Sessions Lead to Increases in"Acceptance"Capacities: A Comparison Study With a Standard 8-Week Mindfulness Training Program. Abstract Source: Front Pharmacol. 2018 ;9:224. Epub 2018 Mar 20. PMID: 29615905 Abstract Author(s): Joaquim Soler, Matilde Elices, Elisabeth Dominguez-Clavé, Juan C Pascual, Amanda Feilding, Mayte Navarro-Gil, Javier García-Campayo, Jordi Riba Article Affiliation: Joaquim Soler Abstract: The therapeutic effects of the Amazonian plant tea ayahuasca may relate to its ability to enhance mindfulness capacities. Ayahuasca induces a modified state of awareness through the combined action of its active principles: the psychedelicdimethyltryptamine (DMT) and a series of centrally actingβ-carbolines, mainly harmine and tetrahydroharmine. To better understand the therapeutic potential of ayahuasca, here we compared the impact on mindfulness capacities induced by two independent interventions: (a) participation in four ayahuasca sessions without any specific purpose related to improving mindfulness capacities; and (b) participation in a standard mindfulness training course: 8 weeks mindfulness-based stress reduction (MBSR), with the specific goal of improving these skills.Participants of two independent groups completed two self-report instruments: The Five Facet Mindfulness Questionnaire (FFMQ) and the Experiences Questionnaire (EQ). The MINDSENS Composite Index was also calculated, including those EQ and FFMQ items that have proven to be the most sensitive to meditation practice. Group A (= 10) was assessed before and after the last of four closely spaced consecutive ayahuasca sessions. Group B (= 10) was assessed before and after completion of a standard 8-week MBSR course.MBSR training led to greater increases in overall mindfulness scores after the 8-week period. MBSR but not ayahuasca led to increases in the MINDSENS Composite Index. However, the ayahuasca sessions induced comparable increases in the Non-Judging subscale of the FFMQ, specifically measuring"acceptance."Improving this capacity allows for a more detached and less judgmental stance toward potentially distressing thoughts and emotions.The present findings suggest that a small number of ayahuasca sessions can be as effective at improving acceptance as more lengthy and costly interventions. Future studies should address the benefits of combining ayahuasca administration with mindfulness-based interventions. This will allow us to investigate if ayahuasca will improve the outcome of psychotherapeutic interventions. Article Published Date : Dec 31, 2017

Effect of mindfulness meditation on short-term weight loss and eating behaviors in overweight and obese adults: A randomized controlled trial.

Abstract Title: Effect of mindfulness meditation on short-term weight loss and eating behaviors in overweight and obese adults: A randomized controlled trial. Abstract Source: J Complement Integr Med. 2017 Dec 5. Epub 2017 Dec 5. PMID: 29211681 Abstract Author(s): Kathleen C Spadaro, Kelliann K Davis, Susan M Sereika, Bethany B Gibbs, John M Jakicic, Susan M Cohen Article Affiliation: Kathleen C Spadaro Abstract: Background There is a significant health crisis with rates of obesity continuing to increase despite research and clinical standard behavioral weight loss programs (SBWP). Mindfulness meditation (MM), with demonstrated benefits on physical, psychological health, and self-regulation behaviors was explored with SBWP. Methods Forty-six adults (BMI=32.5±3.7 kg/m2; age=45.2±8.2 years, 87 % female, 21.7 % African American) were randomly assigned to a 6-month SBWP only (n=24) or SBWP+MM (n=22) at a university-based physical activity and weight management research center in a northeastern US city. Participants were instructed to decrease intake (1200-1500 kcal/day), increase physical activity (300 min/wk), and attend weekly SBWP or SBWP+MM sessions. SBWP+MM had the same SBWP lessons with addition of focused MM training. Outcome measures collected at 0, 3, and 6 months included: weight, Block Food Frequency Questionnaire, Eating BehaviorInventory, Eating Inventory and Paffenbarger Physical Activity Questionnaire. Data were analyzed using linear mixed modeling for efficacy analysis of weight (primary) and eating, exercise and mindfulness (secondary outcomes). Results Retention rate was 76.1 % (n=35). A significant group by time interaction (p=0.03) was found for weight, with weight loss favoring SBWP+MM (-6.9 kg+2.9) over SBWP (-4.1 kg+2.8). Eating behaviors (p=0.02) and dietary restraint (p=0.02) improved significantly in SBWP+MM, compared to SBWP. MM enhanced weight loss by 2.8 kg potentially through greater improvements in eating behaviors and dietary restraint. Conclusions These findings support further study into the use of MM strategies with overweight and obese adults. The use of this low-cost, portable strategy with standard behavioral interventions could improve weight management outcomes. Article Published Date : Dec 04, 2017

Mindfulness mediates the physiological markers of stress: Systematic review and meta-analysis.

Abstract Title: Mindfulness mediates the physiological markers of stress: Systematic review and meta-analysis. Abstract Source: J Psychiatr Res. 2017 Dec ;95:156-178. Epub 2017 Aug 23. PMID: 28863392 Abstract Author(s): Michaela C Pascoe, David R Thompson, Zoe M Jenkins, Chantal F Ski Article Affiliation: Michaela C Pascoe Abstract: Meditation is a popular form of stress management, argued to mediate stress reactivity. However, many studies in this field commonly fail to include an active control group. Given the frequency with which people are selecting meditation as a form of self-management, it is important to validate if the practice is effective in mediating stress-reactivity using well-controlled studies. Thus, we aimed to conduct a meta-analysis investigating the neurobiological effects of meditation, including focused attention, open monitoring and automatic self-transcending subtypes, compared to an active control, on markers of stress. In the current meta-analysis and systematic review, we included randomised controlled trials comparing meditation interventions compared to an active control on physiological markers of stress. Studied outcomes include cortisol, blood pressure, heart-rate, lipids and peripheral cytokine expression. Forty-five studies were included. All meditation subtypes reduced systolic blood pressure. Focused attention meditations also reduced cortisol and open monitoring meditations also reduced heart rate. When all meditation forms were analysed together, meditation reduced cortisol, C - reactive protein, blood pressure, heart rate, triglycerides and tumour necrosis factor-alpha. Overall, meditation practice leads to decreased physiological markers of stress in a range of populations. Article Published Date : Nov 30, 2017

Brief training in mindfulness meditation reduces symptoms in patients with a chronic or recurrent lifetime history of depression: A randomized controlled study.

Abstract Title: Brief training in mindfulness meditation reduces symptoms in patients with a chronic or recurrent lifetime history of depression: A randomized controlled study. Abstract Source: Behav Res Ther. 2017 Oct 12 ;99:124-130. Epub 2017 Oct 12. PMID: 29078199 Abstract Author(s): Emilia Winnebeck, Maria Fissler, Matti Gärtner, Paul Chadwick, Thorsten Barnhofer Article Affiliation: Emilia Winnebeck Abstract: BACKGROUND: Training in mindfulness has been introduced to the treatment of depression as a means of relapse prevention. However, given its buffering effects on maladaptive responses to negative mood, mindfulness training would be expected to be particularly helpful in those who are currently suffering from symptoms. This study investigated whether a brief and targeted mindfulness-based intervention can reduce symptoms in acutely depressed patients. METHODS: Seventy-four patients with a chronic or recurrent lifetime history were randomly allocated to receive either a brief mindfulness-based intervention (MBI) encompassing three individual sessions and regular home practice or a control condition that combined psycho-educational components and regular rest periods using the same format as the MBI. Self-reported severity of symptoms, mindfulness in every day life, ruminative tendencies and cognitive reactivity were assessed before and after intervention. RESULTS: Treatment completers in the MBI condition showed pronounced and significantly stronger reductions in symptoms than those in the control condition. In the MBI group only, patients showed significant increases in mindfulness, and significant reductions in ruminative tendencies and cognitive reactivity. CONCLUSIONS: Brief targeted mindfulness interventions can help to reduce symptoms and buffer maladaptive responses to negative mood in acutely depressed patients with chronic or recurrent lifetime history. Article Published Date : Oct 11, 2017

Mindfulness Meditation Versus Physical Exercise in the Management of Depression Among Nursing Students.

Abstract Title: Mindfulness Meditation Versus Physical Exercise in the Management of Depression Among Nursing Students. Abstract Source: J Nurs Educ. 2017 Oct 1 ;56(10):599-604. PMID: 28972629 Abstract Author(s): Faris Abdelkarim Alsaraireh, Sami Mohammad Aloush Article Affiliation: Faris Abdelkarim Alsaraireh Abstract: BACKGROUND: Depression among nursing students is an ongoing problem. Several psychotherapies have been suggested as alternatives to antidepressants in the management of depression. The aim of this randomized controlled study was to compare the effectiveness of mindfulness meditation versus physical exercise in the management of depression among nursing students. METHOD: A sample of 181 soon-to-graduate nursing students participated in the study and were assigned at random to one of two therapies: physical exercise (n = 90) or mindfulness meditation (n = 91). The Center for Epidemiologic Studies Depression Scale was completed by the participants in both groups prior to the therapies and after completion. RESULTS: The findings indicated that both therapies were effective in the management of depression. However, mindfulness meditation is more effective than physical exercise. CONCLUSION: Mindfulness meditation is recommended over physical exercise in the management of depression among undergraduate nursing students. [J Nurs Educ. 2017;56(10):599-604.]. Article Published Date : Sep 30, 2017

Ancient roots - Modern applications: Mindfulness as a novel intervention for cardiovascular disease.

Abstract Title: Ancient roots - Modern applications: Mindfulness as a novel intervention for cardiovascular disease. Abstract Source: Med Hypotheses. 2017 Oct ;108:57-62. Epub 2017 Aug 4. PMID: 29055403 Abstract Author(s): Gabriel Zieff Article Affiliation: Gabriel Zieff Abstract: Cardiovascular disease (CVD) has been associated with chronic psychological stress. Unremittent psychological stress causes dysregulation of the sympathetic nervous system (SNS) and hypothalamic-pituitaryadrenal (HPA) axis, which collectively promotes inflammation, atherosclerosis, and subsequent CVD risk. Stress reduction techniques, such as mindfulness meditation, have been shown to improve some markers of HPA and SNS function at rest and in response to acute stressors, suggesting that such techniques, over time, may be cardioprotective. Therefore, it may be hypothesized that eight weeks of daily mindfulness meditation, compared to a non-mindful relaxation control, may provide a novel strategy to buffer stress responses in healthy and at-risk populations, thereby lowering the risk of chronic psychological stress and the associated CVD risk as measured by arterial stiffness. The current paper outlines methodological considerations for testing this hypothesis, including appropriate acute stressors, and measurement of SNS, HPA axis and cardiovascular function. If the hypothesis is correct, mindfulness meditation would complement healthy lifestyle techniques such as exercise and diet to prevent CVD risk. Article Published Date : Sep 30, 2017

Mindfulness Meditation for Fibromyalgia: Mechanistic and Clinical Considerations. 📎

Abstract Title: Mindfulness Meditation for Fibromyalgia: Mechanistic and Clinical Considerations. Abstract Source: Curr Rheumatol Rep. 2017 Sep ;19(9):59. PMID: 28752493 Abstract Author(s): Adrienne L Adler-Neal, Fadel Zeidan Article Affiliation: Adrienne L Adler-Neal Abstract: PURPOSE OF REVIEW: Fibromyalgia is a disorder characterized by widespread pain and a spectrum of psychological comorbidities, rendering treatment difficult and often a financial burden. Fibromyalgia is a complicated chronic pain condition that requires a multimodal therapeutic approach to optimize treatment efficacy. Thus, it has been postulated that mind-body techniques may prove fruitful in treating fibromyalgia. Mindfulness meditation, a behavioral technique premised on non-reactive sensory awareness, attenuates pain and improves mental health outcomes. However, the impact of mindfulness meditation on fibromyalgia-related outcomes has not been comprehensively characterized. The present review delineates the existing evidence supporting the effectiveness and hypothesized mechanisms of mindfulness meditation in treating fibromyalgia-related outcomes. RECENT FINDINGS: Mindfulness-based interventions premised on cultivating acceptance, non-attachment, and social engagement may be most effective in decreasing fibromyalgia-related pain and psychological symptoms. Mindfulness-based therapies may alleviate fibromyalgia-related outcomes through multiple neural, psychological, and physiological processes. Mindfulness meditation may provide an effective complementary treatment approach for fibromyalgia patients, especially when combined with other reliable techniques (exercise; cognitive behavioral therapy). However, characterizing the specific analgesic mechanisms supporting mindfulness meditation is a critical step to fostering the clinical validity of this technique. Identification of the specific analgesic mechanisms supporting mindfulness-based pain relief could be utilized to better design behavioral interventions to specifically target fibromyalgia-related outcomes. Article Published Date : Aug 31, 2017

Mindfulness and pharmacological prophylaxis have comparable effect on biomarkers of inflammation and clinical indexes in chronic migraine with medication overuse: results at 12 months after withdrawal.

Abstract Title: Mindfulness and pharmacological prophylaxis have comparable effect on biomarkers of inflammation and clinical indexes in chronic migraine with medication overuse: results at 12 months after withdrawal. Abstract Source: Neurol Sci. 2017 May ;38(Suppl 1):173-175. PMID: 28527073 Abstract Author(s): Licia Grazzi, Domenico D'Amico, Alberto Raggi, Matilde Leonardi, Emilio Ciusani, Elena Corsini, Giovanni D'Andrea, Andrea Bolner, Francisco Salgado-García, Frank Andrasik, Emanuela Sansone Article Affiliation: Licia Grazzi Abstract: Chronic migraine (CM) is a disabling condition arising from a complex mixture of interconnected biological, psychological and social factors, and is often associated with medication overuse (MO). Mindfulness is emerging as a helpful treatment for pain, and one study showed that the longitudinal 12 months' course of CM-MO patients that attended mindfulness-based treatment alone was similar to that of patients receiving medical prophylaxis alone; in this study, we describe the course of biomarkers of inflammation. Our results provide initial evidence of sustained similar effects on reduced concentration of biomarkers of inflammation, although not sizeable enough to reach statistical significance. Whether more intensive treatment and/or larger samples would lead to greater changes is unknown, but these encouraging preliminary findings suggest further research is warranted. Article Published Date : Apr 30, 2017

Mindfulness practice reduces cortisol blunting during chemotherapy: A randomized controlled study of colorectal cancer patients.

Abstract Title: Mindfulness practice reduces cortisol blunting during chemotherapy: A randomized controlled study of colorectal cancer patients. Abstract Source: Cancer. 2017 Apr 7. Epub 2017 Apr 7. PMID: 28387949 Abstract Author(s): David S Black, Cheng Peng, Alix G Sleight, Nathalie Nguyen, Heinz-Josef Lenz, Jane C Figueiredo Article Affiliation: David S Black Abstract: BACKGROUND: The objective of this randomized clinical experiment was to test the influence of a mindfulness meditation practice, when delivered during 1 session of active chemotherapy administration, on the acute salivary cortisol response as a marker of neuroendocrine system activity in cancer patients. METHODS: A mindfulness, attention-control, or resting exposure was assigned to 57 English- or Spanish-speaking colorectal cancer patients at 1 county oncology clinic and 1 university oncology clinic at the start of chemotherapy. Saliva samples were collected at the start of chemotherapy and at subsequent 20-minute intervals during the first 60 minutes of chemotherapy (4 samples in all). Self-reporting on biobehavioral assessments after chemotherapy included distress, fatigue, and mindfulness. RESULTS: An area-under-the-curve analysis (AUC) showed a relative increase in cortisol reactivity in the mindfulness group after adjustments for biological and clinical measures (β = 123.21; P = .03). More than twice as many patients in the mindfulness group versus the controls displayed a cortisol rise from the baseline to 20 minutes (69% vs 34%; P = .02). AUC values were uncorrelated with biobehavioral measure scores, although mindfulness scores were inverselycorrelated with fatigue (r = -0.46; P < .01) and distress scores (r = -0.54; P < .01). CONCLUSIONS: Findings suggest that mindfulness practice during chemotherapy can reduce the blunting of neuroendocrine profiles typically observed in cancer patients. Implications include support for the use of mindfulness practice in integrative oncology. Cancer 2017.© 2017 American Cancer Society. Article Published Date : Apr 06, 2017

Mind-Body Interventions for Pediatric Inflammatory Bowel Disease. 📎

Abstract Title: Mind-Body Interventions for Pediatric Inflammatory Bowel Disease. Abstract Source: Children (Basel). 2017 Apr 3 ;4(4). Epub 2017 Apr 3. PMID: 28368365 Abstract Author(s): Ann Ming Yeh, Anava Wren, Brenda Golianu Article Affiliation: Ann Ming Yeh Abstract: Pediatric inflammatory bowel disease is an autoimmune disease that causes chronic inflammation of the gastrointestinal mucosa. There is emerging evidence that the brain-gut connection affects inflammatory bowel disease (IBD) patients more than previously thought. This is evidenced by comorbid mood disorders, irritable bowel symptoms concurrent with quiescent IBD, and the potential of psychosocial stressors to trigger IBD flares. Mind-body interventions such as psychotherapy, relaxation, mindfulness, biofeedback, yoga, and clinical hypnosis offer an adjunct to standard medical treatment for IBD. We will review the current evidence base for these mind- body interventions in the treatment of pediatric IBD, illustrate a case study, and offer suggestions for future research for this promising field. Article Published Date : Apr 02, 2017

A randomised controlled study of mindfulness meditation versus relaxation therapy in the management of tinnitus.

Abstract Title: A randomised controlled study of mindfulness meditation versus relaxation therapy in the management of tinnitus. Abstract Source: J Laryngol Otol. 2017 Mar 30:1-7. Epub 2017 Mar 30. PMID: 28357966 Abstract Author(s): M Arif, M Sadlier, D Rajenderkumar, J James, T Tahir Article Affiliation: M Arif Abstract: OBJECTIVE: Psychotherapeutic interventions have been adopted effectively in the management of tinnitus for a long time. This study compared mindfulness meditation and relaxation therapy for management of tinnitus. METHODS: In this randomised controlled trial, patients were recruited for five sessions of mindfulness meditation or five sessions of relaxation therapy. Patients' responses were evaluated using the Tinnitus Reaction Questionnaire as a primary outcome measure, and the Hospital Anxiety and Depression Scale, visual analogue scale and a health status indicator as secondary outcome measures. RESULTS: A total of 86 patients were recruited. Thirty-four patients completed mindfulness meditation and 27 patients completed relaxation therapy. Statistically significant improvement was seen in all outcome measures except the health status indicator in both treatment groups. The change in treatment scores was greater in the mindfulness meditation group than in the relaxation therapy group. CONCLUSION: This study suggests that although both mindfulness meditation and relaxation therapy are effective in the management of tinnitus, mindfulness meditation is superior to relaxation therapy. Article Published Date : Mar 29, 2017

The embodied mind: A review on functional genomic and neurological correlates of mind-body therapies.

Abstract Title: The embodied mind: A review on functional genomic and neurological correlates of mind-body therapies. Abstract Source: Neurosci Biobehav Rev. 2017 Feb ;73:165-181. Epub 2016 Dec 23. PMID: 28017838 Abstract Author(s): David Muehsam, Susan Lutgendorf, Paul J Mills, Badri Rickhi, Gaétan Chevalier, Namuun Bat, Deepak Chopra, Blake Gurfein Article Affiliation: David Muehsam Abstract: A broad range of mind-body therapies (MBTs) are used by the public today, and a growing body of clinical and basic sciences research has resulted in evidence-based integration of many MBTs into clinical practice. Basic sciences research has identified some of the physiological correlates of MBT practices, leading to a better understanding of the processes by which emotional, cognitive and psychosocial factors can influence health outcomes and well-being. In particular, results from functional genomics and neuroimaging describe some of the processes involved in the mind-body connection and how these can influence health outcomes. Functional genomic and neurophysiological correlates of MBTs are reviewed, detailing studies showing changes in sympathetic nervous system activation of gene transcription factors involved in immune function and inflammation, electroencephalographic and neuroimaging studies on MBT practices, and persistent changes in neural function and morphology associated with these practices. While the broad diversity of study designs and MBTs studied presents a patchwork of results requiring further validation through replication and longitudinal studies, clear themes emerge for MBTs as immunomodulatory, with effects on leukocyte transcription and function related to inflammatory and innate immune responses, and neuromodulatory, with effects on brain function and morphology relevant for attention, learning, and emotion regulation. By detailing the potential mechanisms of action by which MBTs may influence health outcomes, the data generated by these studies have contributed significantly towards a better understanding of the biological mechanisms underlying MBTs. Article Published Date : Jan 31, 2017

Promising Links between Meditation and Reduced (Brain) Aging: An Attempt to Bridge Some Gaps between the Alleged Fountain of Youth and the Youth of the Field. 📎

Abstract Title: Promising Links between Meditation and Reduced (Brain) Aging: An Attempt to Bridge Some Gaps between the Alleged Fountain of Youth and the Youth of the Field. Abstract Source: Front Psychol. 2017 ;8:860. Epub 2017 May 30. PMID: 28611710 Abstract Author(s): Florian Kurth, Nicolas Cherbuin, Eileen Luders Article Affiliation: Florian Kurth Abstract: Over the last decade, an increasing number of studies has reported a positive impact of meditation on cerebral aging. However, the underlying mechanisms for these seemingly brain-protecting effects are not well-understood. This may be due to the fact, at least partly, that systematic empirical meditation research has emerged only recently as a field of scientific scrutiny. Thus, on the one hand, critical questions remain largely unanswered; and on the other hand, outcomes of existing research require better integration to build a more comprehensive and holistic picture. In this article, we first review theories and mechanisms pertaining to normal (brain) aging, specifically focusing on telomeres, inflammation, stress regulation, and macroscopic brain anatomy. Then, we summarize existing research integrating the developing evidence suggesting that meditation exerts positive effects on (brain) aging, while carefully discussing possible mechanisms through which these effects may be mediated. Article Published Date : Dec 31, 2016

Brief mindfulness training reduces salivary IL-6 and TNF-α in young women with depressive symptomatology. 📎

Abstract Title: Brief mindfulness training reduces salivary IL-6 and TNF-α in young women with depressive symptomatology. Abstract Source: J Consult Clin Psychol. 2016 Oct ;84(10):887-97. Epub 2016 Jun 9. PMID: 27281371 Abstract Author(s): Erin Walsh, Tory Eisenlohr-Moul, Ruth Baer Article Affiliation: Erin Walsh Abstract: OBJECTIVE: Pro-inflammatory cytokines have been implicated in the pathophysiology and maintenance of depression. This study investigated the effects of a brief mindfulness intervention on salivary pro-inflammatory correlates of depression (IL-6, TNF-α) and self-reported symptoms of depression in college women. METHODS: Sixty-four females with a cut score of≥16 on the Center for Epidemiological Studies for Depression Scale (CES-D) were assigned to a 4-week mindfulness-based intervention (MBI; N = 31) or a contact-control group (N = 33). For both groups, salivary cytokines and depressive symptoms were assessed at baseline and posttreatment. For the mindfulness group only, salivary cytokines were also assessed at a 3-month follow-up. RESULTS: Both groups showed similar reductions in depression. However, MBI (vs. control) predicted greater reductions in IL-6 and TNF-α; changes in IL-6 were sustained at 3-month follow-up. Higher baseline depressive symptoms predicted greater reductions in inflammation in the mindfulness group. CONCLUSION: MBIs may reduce inflammatory immune markers commonly implicated in depression. Individuals with greater depressive symptoms may benefit more from mindfulness training. Although reductions in salivary cytokines in the mindfulness condition were not attributable to changes in depressive symptoms, future work should examine the possibility that such reductions are protective against the development of future depressive episodes. (PsycINFO Database Record Article Published Date : Sep 30, 2016
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Preventing and Alleviating Compassion Fatigue Through Self-Care: An Educational Workshop for Nurses.

Related Articles Preventing and Alleviating Compassion Fatigue Through Self-Care: An Educational Workshop for Nurses. J Holist Nurs. 2018 Dec;36(4):304-317 Authors: Adimando A Abstract Though various authors have refined and described the concept of compassion fatigue (CF), the overarching features, predisposing factors, and potential consequences remain relatively consistent. Available literature demonstrates that caregivers caring for patients who are chronically ill and/or traumatized are at highest risk for developing CF. Potential consequences for unmitigated CF include physical, emotional, and work-related consequences, all of which can have negative effects on the quality and safety of care and degree of engagement with one's employer. CF is further exacerbated by exposure to cumulative, unresolved stress and neglect of one's own emotional needs over time. Caregivers must be knowledgeable on CF's risk factors, symptoms, and management strategies to decrease its incidence and negative impacts. This article details the creation, execution, and evaluation of an evidence-based practice change project implemented with the goal of increasing knowledge needed to prevent, identify, and alleviate CF in high-risk nurses. The project involved a series of educational workshops containing information on CF's risk factors, symptoms, and consequences, with a strong emphasis on self-awareness, self-care, and stress management. Pre- and postknowledge tests showed a significant increase in knowledge was achieved via the workshops, and qualitative surveys indicated a high level of participant satisfaction with the program contents, format, and impact. PMID: 28766396 [PubMed - indexed for MEDLINE]
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