CYBERMED LIFE - ORGANIC  & NATURAL LIVING

Respiratory Syncytial Virus Infections

  • Investigation of the influence of EPs® 7630, a herbal drug preparation from Pelargonium sidoides, on replication of a broad panel of respiratory viruses.

    Abstract Title:

    Investigation of the influence of EPs® 7630, a herbal drug preparation from Pelargonium sidoides, on replication of a broad panel of respiratory viruses.

    Abstract Source:

    Phytomedicine. 2010 Oct 29. Epub 2010 Oct 29. PMID: 21036571

    Abstract Author(s):

    Martin Michaelis, Hans Wilhelm Doerr, Jindrich Cinatl

    Article Affiliation:

    Institut für Medizinische Virologie, Klinikum der J.W. Goethe-Universität, 60596 Frankfurt am Main, Germany.

    Abstract:

    The Pelargonium sidoides extract EPs(®) 7630 is an approved drug for the treatment of acute bronchitis in Germany. The postulated mechanisms underlying beneficial effects of EPs(®) 7630 in bronchitis patients include immunomodulatory and cytoprotective effects, inhibition of interaction between bacteria and host cells, and increase of cilliary beat frequency on respiratory cells. Here, we investigated the influence of EPs(®) 7630 on replication of a panel of respiratory viruses. Determination of virus-induced cytopathogenic effects and virus titres revealed that EPs(®) 7630 at concentrations up to 100μg/ml interfered with replication of seasonal influenza A virus strains (H1N1, H3N2), respiratory syncytial virus, human coronavirus, parainfluenza virus, and coxsackie virus but did not affect replication of highly pathogenic avian influenza A virus (H5N1), adenovirus, or rhinovirus. Therefore, antiviral effects may contribute to the beneficial effects exerted by EPs(®) 7630 in acute bronchitis patients.

    Article Published Date : Oct 29, 2010

  • Investigation of the influence of EPs® 7630, a herbal drug preparation from Pelargonium sidoides, on replication of a broad panel of respiratory viruses.

    Abstract Title:

    Investigation of the influence of EPs® 7630, a herbal drug preparation from Pelargonium sidoides, on replication of a broad panel of respiratory viruses.

    Abstract Source:

    Phytomedicine. 2010 Oct 29. Epub 2010 Oct 29. PMID: 21036571

    Abstract Author(s):

    Martin Michaelis, Hans Wilhelm Doerr, Jindrich Cinatl

    Article Affiliation:

    Institut für Medizinische Virologie, Klinikum der J.W. Goethe-Universität, 60596 Frankfurt am Main, Germany.

    Abstract:

    The Pelargonium sidoides extract EPs(®) 7630 is an approved drug for the treatment of acute bronchitis in Germany. The postulated mechanisms underlying beneficial effects of EPs(®) 7630 in bronchitis patients include immunomodulatory and cytoprotective effects, inhibition of interaction between bacteria and host cells, and increase of cilliary beat frequency on respiratory cells. Here, we investigated the influence of EPs(®) 7630 on replication of a panel of respiratory viruses. Determination of virus-induced cytopathogenic effects and virus titres revealed that EPs(®) 7630 at concentrations up to 100μg/ml interfered with replication of seasonal influenza A virus strains (H1N1, H3N2), respiratory syncytial virus, human coronavirus, parainfluenza virus, and coxsackie virus but did not affect replication of highly pathogenic avian influenza A virus (H5N1), adenovirus, or rhinovirus. Therefore, antiviral effects may contribute to the beneficial effects exerted by EPs(®) 7630 in acute bronchitis patients.

    Article Published Date : Oct 29, 2010

  • Investigation of the influence of EPs® 7630, a herbal drug preparation from Pelargonium sidoides, on replication of a broad panel of respiratory viruses.

    Abstract Title:

    Investigation of the influence of EPs® 7630, a herbal drug preparation from Pelargonium sidoides, on replication of a broad panel of respiratory viruses.

    Abstract Source:

    Phytomedicine. 2010 Oct 29. Epub 2010 Oct 29. PMID: 21036571

    Abstract Author(s):

    Martin Michaelis, Hans Wilhelm Doerr, Jindrich Cinatl

    Article Affiliation:

    Institut für Medizinische Virologie, Klinikum der J.W. Goethe-Universität, 60596 Frankfurt am Main, Germany.

    Abstract:

    The Pelargonium sidoides extract EPs(®) 7630 is an approved drug for the treatment of acute bronchitis in Germany. The postulated mechanisms underlying beneficial effects of EPs(®) 7630 in bronchitis patients include immunomodulatory and cytoprotective effects, inhibition of interaction between bacteria and host cells, and increase of cilliary beat frequency on respiratory cells. Here, we investigated the influence of EPs(®) 7630 on replication of a panel of respiratory viruses. Determination of virus-induced cytopathogenic effects and virus titres revealed that EPs(®) 7630 at concentrations up to 100μg/ml interfered with replication of seasonal influenza A virus strains (H1N1, H3N2), respiratory syncytial virus, human coronavirus, parainfluenza virus, and coxsackie virus but did not affect replication of highly pathogenic avian influenza A virus (H5N1), adenovirus, or rhinovirus. Therefore, antiviral effects may contribute to the beneficial effects exerted by EPs(®) 7630 in acute bronchitis patients.

    Article Published Date : Oct 29, 2010

  • The "Dark Evil"

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    Prof. Dott. Giulio Tarro Phd MD

    I have always been keen on the story of my fellow countryman "colleague": the protomedico Giovanni Filippo Ingrassia who faced the plague epidemic (1575-76) of Palermo containing its effects: three thousand deaths. Very little compared to eighteen thousand in Milan and thirty thousand in Genoa. Years before, he had already proved himself identifying in the swamp lands, fed by the river Papireto, which surrounded the city of Palermo the cause of malaria. Obviously, without knowing anything - given the time - of Plasmodium malariae and how this was transmitted by mosquitoes. But reflecting on how this infection spread among the population. Unfortunately for him he did not see the results of his intuitions: only in 1591 (11 years after his death) the praetor Salazar had the river Papireto channelled determining the disappearance of malaria from Palermo.