The NSAID (non-steroidal, anti-inflammatory drugs) painkillers make Clostridium difficile infection more likely, and worsen the symptoms, which can include diarrhea, stomach pains and fatigue; it's also one of the most dangerous infections caught in hospitals and care homes, with the US's Centers for Disease Control and Prevention (CDC) estimating that 15,000 Americans die each year as a direct result of infection.