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Anti-inflammatory activity of Arnica montana 6cH: preclinical study in animals.

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Abstract Title:

Anti-inflammatory activity of Arnica montana 6cH: preclinical study in animals.

Abstract Source:

Homeopathy. 2004 Apr;93(2):84-7. PMID: 15139092

Abstract Author(s):

S B Macêdo, L R Ferreira, F F Perazzo, J C Carvalho

Article Affiliation:

Faculdade de Odontologia, Pontificia Universidade Católica de Brasília, Brasília, Brazil.

Abstract:

The anti-inflammatory effect of Arnica montana 6cH was evaluated using acute and chronic inflammation models. In the acute, model, carrageenin-induced rat paw oedema, the group treated with Arnica montana 6cH showed 30% inhibition compared to control (P<0.05). Treatment with Arnica 6cH, 30 min prior to carrageenin, did not produce any inhibition of the inflammatory process. In the chronic model, Nystatin-induced oedema, the group treated 3 days previously with Arnica montana 6cH had reduced inflammation 6 h after the inflammatory agent was applied (P<0.05). When treatment was given 6 h after Nystatin treatment, there was no significant inhibitory effect. In a model based on histamine-induced increase of vascular permeability, pretreatment with Arnica montana 6cH blocked the action of histamine in increasing vascular permeability.


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