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Antiviral Substances in Raw Bovine Milk Active Against Bovine Rotavirus and Coronavirus📎

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Abstract Title:

Antiviral Substances in Raw Bovine Milk Active Against Bovine Rotavirus and Coronavirus.

Abstract Source:

J Food Prot. 1987 Oct ;50(10):862-866. PMID: 30978786

Abstract Author(s):

G Panon, S Tache, C Labie

Article Affiliation:

G Panon

Abstract:

After experimental contamination of bovine raw and heat-treated milks with bovine rotavirus and coronavirus strains, we observed a strong viral inhibition only with raw milks, from which virus recovery was 5× 10%. Between 30% and 80% of the virus was recovered from the heat-treated milks, depending on the level of inoculation. The antiviral substance is heat-labile (destroyed within 30 min at 100°C), precipitated by ammonium sulfate and filtrable (0.45 μm Millipore membrane). It also has neutralizing activity on tissue culture.