CYBERMED LIFE - ORGANIC  & NATURAL LIVING

Nocebo Effect

  • Fear-driven cesarean section on request

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    Abstract Title:

    [Fear-driven cesarean section on request].

    Abstract Source:

    Pol Merkur Lekarski. 2012 Aug ;33(194):86-9. PMID: 23009005

    Abstract Author(s):

    Małgorzata Pawelec, Jolanta Pietras, Andrzej Karmowski, Bogusław Pałczyński, Mikołaj Karmowski, Tytus Nowak

    Article Affiliation:

    First Chair and Department of Gynecology and Obstetrics, Medical University of Wroclaw, Poland. This email address is being protected from spambots. You need JavaScript enabled to view it.

    Abstract:

    UNLABELLED:Traditionally, women gave birth surrounded by other, experienced women. Modern women not only require continuous support during labor, but they also want to have a part in decision-taking. That is why some of them, regardless of how much or how little medical knowledge they have, want to decide about the way of birth on their own. The aim of this study was to find the underlying cause of the growing percentage of cesarean sections and cesarean sections on request and to find an answer to the question of what can be done to reduce that number.

    MATERIAL AND METHODS:A survey was conducted among 100 nulliparas between 38 and 40 week of pregnancy who were determined to give birth in a natural way, and among 50 nulliparas, in the same gestational age, who requested cesarean section.

    RESULTS:The analysis of our survey shows that request for cesarean section in 12% of cases resulted from fear of labor pain, more than before were declared 2%. After they were informed about methods of reducing labor pain and guaranteed that those methods would be available, as many as 52% of pregnant women who had previously requested cesarean section changed their mind and wanted to give birth in a natural way (this could reduce cesarean section rate about 52%, p<0.05), and 42% (of the total) wanted to have epidural anesthesia.

    CONCLUSIONS:Better access of pregnant women to information about pharmacological and non-pharmacological methods of reducing labor pain, coupled with the availability of those methods, can reduce the number of cesarean sections on request even by half. In the group of pregnant women determined to have cesarean section, one in four would give it up if they had access to epidural anesthesia, and one in ten if they had access to non-pharmacological methods of reducing labor pain (mainly acupuncture).

  • Fear-driven cesarean section on request

    facebook Share on Facebook
    Abstract Title:

    [Fear-driven cesarean section on request].

    Abstract Source:

    Pol Merkur Lekarski. 2012 Aug ;33(194):86-9. PMID: 23009005

    Abstract Author(s):

    Małgorzata Pawelec, Jolanta Pietras, Andrzej Karmowski, Bogusław Pałczyński, Mikołaj Karmowski, Tytus Nowak

    Article Affiliation:

    First Chair and Department of Gynecology and Obstetrics, Medical University of Wroclaw, Poland. This email address is being protected from spambots. You need JavaScript enabled to view it.

    Abstract:

    UNLABELLED:Traditionally, women gave birth surrounded by other, experienced women. Modern women not only require continuous support during labor, but they also want to have a part in decision-taking. That is why some of them, regardless of how much or how little medical knowledge they have, want to decide about the way of birth on their own. The aim of this study was to find the underlying cause of the growing percentage of cesarean sections and cesarean sections on request and to find an answer to the question of what can be done to reduce that number.

    MATERIAL AND METHODS:A survey was conducted among 100 nulliparas between 38 and 40 week of pregnancy who were determined to give birth in a natural way, and among 50 nulliparas, in the same gestational age, who requested cesarean section.

    RESULTS:The analysis of our survey shows that request for cesarean section in 12% of cases resulted from fear of labor pain, more than before were declared 2%. After they were informed about methods of reducing labor pain and guaranteed that those methods would be available, as many as 52% of pregnant women who had previously requested cesarean section changed their mind and wanted to give birth in a natural way (this could reduce cesarean section rate about 52%, p<0.05), and 42% (of the total) wanted to have epidural anesthesia.

    CONCLUSIONS:Better access of pregnant women to information about pharmacological and non-pharmacological methods of reducing labor pain, coupled with the availability of those methods, can reduce the number of cesarean sections on request even by half. In the group of pregnant women determined to have cesarean section, one in four would give it up if they had access to epidural anesthesia, and one in ten if they had access to non-pharmacological methods of reducing labor pain (mainly acupuncture).

  • Induction of nocebo and placebo effects on itch and pain by verbal suggestions.

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    Abstract Title:

    Induction of nocebo and placebo effects on itch and pain by verbal suggestions.

    Abstract Source:

    Pain. 2011 Jul;152(7):1486-94. Epub 2011 Feb 24. PMID: 21353388

    Abstract Author(s):

    Antoinette I M van Laarhoven, Michiel L Vogelaar, Oliver H Wilder-Smith, Piet L C M van Riel, Peter C M van de Kerkhof, Floris W Kraaimaat, Andrea W M Evers

    Article Affiliation:

    Department of Medical Psychology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

    Abstract:

    Physical complaints, such as pain, can be effectively reduced by placebo effects through induction of positive expectations, or increased by nocebo effects through induction of negative expectations. In the present study, verbally induced nocebo and placebo effects on itch were experimentally investigated for the first time. In part 1, the role of verbal suggestions in inducing nocebo effects on itch and pain was investigated. All subjects received the same somatosensory quantitative sensory testing stimuli, that is, mechanical and electrical stimuli and application of histamine, and verbal suggestions to manipulate expectations regarding the stimuli. The suggestions were designed to produce either high expectations for itch (itch nocebo) or pain (pain nocebo) or low expectations for itch (itch nocebo control) or pain (pain nocebo control). Results showed that high itch and pain expectations resulted in higher levels of itch and pain, respectively. When comparing nocebo effects, induced by verbal suggestions, results were more pronounced for itch than for pain. In part 2, verbal suggestions designed to produce a placebo effect on itch (itch placebo) or pain (pain placebo), or neutral suggestions (itch placebo control and pain placebo control) were given regarding a second application of histamine and compared with the first application applied in part 1. Results of placebo effects only showed a significantly larger decrease in itch in the itch placebo condition than in the pain placebo condition. In conclusion, we showed for the first time that nocebo and possibly placebo responses can be induced on itch by verbal suggestions. Experiments of nocebo and placebo effects on itch and pain demonstrated that particularly nocebo effects can be induced on itch and pain by verbal suggestions.

  • Practitioner empathy and the duration of the common cold. 📎

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    Abstract Title:

    Practitioner empathy and the duration of the common cold.

    Abstract Source:

    Fam Med. 2009 Jul-Aug;41(7):494-501. PMID: 19582635

    Abstract Author(s):

    David P Rakel, Theresa J Hoeft, Bruce P Barrett, Betty A Chewning, Benjamin M Craig, Min Niu

    Article Affiliation:

    School of Medicine and Public Health, University of Wisconsin, Madison, WI 53715, USA. This email address is being protected from spambots. You need JavaScript enabled to view it.

    Abstract:

    OBJECTIVE:This study's objective was to assess the relationship of empathy in medical office visits to subsequent outcomes of the common cold.

    METHODS:A total of 350 subjects ? 12 years of age received either a standard or enhanced physician visit as part of a randomized controlled trial. Enhanced visits emphasized empathy on the part of the physician. The patient-scored Consultation and Relational Empathy (CARE) questionnaire assessed practitioner-patient interaction, especially empathy. Cold severity and duration were assessed from twice-daily symptom reports. Nasal wash was performed to measure the immune cytokine interleukin-8 (IL-8).

    RESULTS:Eighty-four individuals reported perfect (score of 50) CARE scores. They tended to be older with less education but reported similar health status, quality of life, and levels of optimism. In those with perfect CARE scores, cold duration was shorter (mean 7.10 days versus 8.01 days), and there was a trend toward reduced severity (mean area under receiver-operator characteristics curve 240.40 versus 284.49). After accounting for possible confounding variables, cold severity and duration were significantly lower in those reporting perfect CARE scores. In these models, a perfect score also correlated with a larger increase in IL-8 levels.

    CONCLUSIONS:Clinician empathy, as perceived by patients with the common cold, significantly predicts subsequent duration and severity of illness and is associated with immune system changes.

  • Practitioner empathy and the duration of the common cold. 📎

    facebook Share on Facebook
    Abstract Title:

    Practitioner empathy and the duration of the common cold.

    Abstract Source:

    Fam Med. 2009 Jul-Aug;41(7):494-501. PMID: 19582635

    Abstract Author(s):

    David P Rakel, Theresa J Hoeft, Bruce P Barrett, Betty A Chewning, Benjamin M Craig, Min Niu

    Article Affiliation:

    School of Medicine and Public Health, University of Wisconsin, Madison, WI 53715, USA. This email address is being protected from spambots. You need JavaScript enabled to view it.

    Abstract:

    OBJECTIVE:This study's objective was to assess the relationship of empathy in medical office visits to subsequent outcomes of the common cold.

    METHODS:A total of 350 subjects ? 12 years of age received either a standard or enhanced physician visit as part of a randomized controlled trial. Enhanced visits emphasized empathy on the part of the physician. The patient-scored Consultation and Relational Empathy (CARE) questionnaire assessed practitioner-patient interaction, especially empathy. Cold severity and duration were assessed from twice-daily symptom reports. Nasal wash was performed to measure the immune cytokine interleukin-8 (IL-8).

    RESULTS:Eighty-four individuals reported perfect (score of 50) CARE scores. They tended to be older with less education but reported similar health status, quality of life, and levels of optimism. In those with perfect CARE scores, cold duration was shorter (mean 7.10 days versus 8.01 days), and there was a trend toward reduced severity (mean area under receiver-operator characteristics curve 240.40 versus 284.49). After accounting for possible confounding variables, cold severity and duration were significantly lower in those reporting perfect CARE scores. In these models, a perfect score also correlated with a larger increase in IL-8 levels.

    CONCLUSIONS:Clinician empathy, as perceived by patients with the common cold, significantly predicts subsequent duration and severity of illness and is associated with immune system changes.

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