Following the severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV), another highly pathogenic coronavirus named SARS-CoV-2 (previously known as 2019-nCoV) emerged in December 2019 in Wuhan, China, and rapidly spreads around the world. This virus shares highly homological sequence with SARS-CoV, and causes acute, highly lethal pneumonia coronavirus disease 2019 (COVID-19) with clinical symptoms similar to those reported for SARS-CoV and MERS-CoV. The most characteristic symptom of patients with COVID-19 is respiratory distress, and most of the patients admitted to the intensive care could not breathe spontaneously. Additionally, some patients with COVID-19 also showed neurologic signs, such as headache, nausea, and vomiting. Increasing evidence shows that coronaviruses are not always confined to the respiratory tract and that they may also invade the central nervous system inducing neurological diseases. The infection of SARS-CoV has been reported in the brains from both patients and experimental animals, where the brainstem was heavily infected. Furthermore, some coronaviruses have been demonstrated able to spread via a synapse-connected route to the medullary cardiorespiratory center from the mechanoreceptors and chemoreceptors in the lung and lower respiratory airways. Considering the high similarity between SARS-CoV and SARS-CoV2, it remains to make clear whether the potential invasion of SARS-CoV2 is partially responsible for the acute respiratory failure of patients with COVID-19. Awareness of this may have a guiding significance for the prevention and treatment of the SARS-CoV-2-induced respiratory failure.

The spread of COVID-19 continues in China and in the world as the World Health Organization (WHO) baptized it, warned since 31-12-2019 of the new SARS (Severe Acute Respiratory Syndrome). The epidemic has its own basic reproduction number, Ro, which is considered less than 1 when it runs out of passage from one individual to another and tends to rise as in the previous SARS epidemic (2002-2003) between 2 and 4 to get to measles with values of 12-18. The current Ro is estimated between 2 and 3. More than 86 thousand are infected today 03-3-2020, with almost 3 thousand deaths. Flights to China have been suspended, while seasonal flu has infected and killed more people.

The spread of COVID-19 continues in China and in the world as the World Health Organization (WHO) baptized it, warned since 31-12-2019 of the new SARS (Severe Acute Respiratory Syndrome).
The epidemic has its own basic reproduction number, Ro, which is considered less than 1 when it runs out of passage from one individual to another and tends to rise as in the previous SARS epidemic (2002-2003) between 2 and 4 to get to measles with values of 12-18. The current Ro is estimated between 2 and 3. More than 86 thousand are infected today 03-3-2020, with almost 3 thousand deaths.
Flights to China have been suspended, while seasonal flu has infected and killed more people.

The spread of COVID-19 continues in China and in the world as the World Health Organization (WHO) baptized it, warned since 31-12-2019 of the new SARS (Severe Acute Respiratory Syndrome).
The epidemic has its own basic reproduction number, Ro, which is considered less than 1 when it runs out of passage from one individual to another and tends to rise as in the previous SARS epidemic (2002-2003) between 2 and 4 to get to measles with values of 12-18. The current Ro is estimated between 2 and 3. More than 86 thousand are infected today 03-3-2020, with almost 3 thousand deaths.
Flights to China have been suspended, while seasonal flu has infected and killed more people.

The spread of COVID-19 continues in China and in the world as the World Health Organization (WHO) baptized it, warned since 31-12-2019 of the new SARS (Severe Acute Respiratory Syndrome).
The epidemic has its own basic reproduction number, Ro, which is considered less than 1 when it runs out of passage from one individual to another and tends to rise as in the previous SARS epidemic (2002-2003) between 2 and 4 to get to measles with values of 12-18. The current Ro is estimated between 2 and 3. More than 86 thousand are infected today 03-3-2020, with almost 3 thousand deaths.
Flights to China have been suspended, while seasonal flu has infected and killed more people.

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The effect of H2O2 on adenovirus types 3 and 6, adenoassociated virus type 4, rhinoviruses 1A, 1B, and type 7, myxoviruses, influenza A and B, respiratory syncytial virus, strain Long, and coronavirus strain 229E was studied in vitro, using different H2O2 concentration and timec of exposure. H2O2 in a 3 percent concentration inactivated all the viruses under study within 1--30 min. Coronavirus and influenza viruses were found to be most sensitive. Reoviruses, adenoviruses and adenoassociated virus were relatively stable. H2O2 is a convenient means for virus inactivation.

There is anecdotal evidence that tocilizumab, an immunosuppressant drug, may be a potential therapeutic option for patients with severe manifestations of coronavirus disease 2019 (COVID-19). Like tocilizumab, Vitamin D appears to modulate the activity of an interleukin (IL-6), which may explain the seasonal variation in prevalence of influenza. While most cases of COVID-19 have, thus far, occurred in the Northern Hemisphere winter, limiting the ability to assess seasonal variation, there remains substantial variation in the severity of this condition that has yet to be explained. A retrospective comparison of Vitamin D levels in previously obtained blood samples between survivors and confirmed fatalities could establish a rationale for implementation of widespread Vitamin D supplementation. This would be far cheaper and simpler than tocilizumab as a therapeutic option to trial.