Abstract Title: Leukocyte telomere length and marital status among middle-aged adults. Abstract Source: Age Ageing. 2011 Jan ;40(1):73-8. Epub 2010 Sep 4. PMID: 20817935 Abstract Author(s): Arch G Mainous, Charles J Everett, Vanessa A Diaz, Richard Baker, Massimo Mangino, Veryan Codd, Nilesh J Samani Article Affiliation: Medical University of South Carolina, Family Medicine, Charleston, SC 29425, USA. This email address is being protected from spambots. You need JavaScript enabled to view it. Abstract: BACKGROUND: being unmarried is associated with worse health and increased mortality risk. Telomere length has emerged as a marker for biological ageing but it is unclear how telomere length relates to marital status. OBJECTIVE: to examine the relationship between telomere length and marital status in a sample of middle-aged adults. Design and subjects: cross-sectional analysis among 321 adults aged 40-64 years. METHODS: telomere length was measured by PCR (T/S ratio). Participants provided information on healthy lifestyle activities including smoking, alcohol use, diet, exercise, obesity as well as social support. RESULTS: participants married or living with a partner had a mean T/S ratio of 1.70 and those widowed, divorced, separated or never married had a mean T/S ratio of 1.58 in a model adjusted for age, gender and race/ethnicity (P<0.001). When the analysis was further adjusted for diet, alcohol consumption, exercise, smoking, social support, poverty and obesity, persons married or living with a partner had a higher mean T/S ratio of 1.69 than their unmarried counterparts (1.59) (P = 0.004). CONCLUSIONS: these results indicate that unmarried individuals have shorter telomeres. This relationship between marital status and telomere length is independent of presumed benefits of marriage such as social support and a healthier lifestyle. Article Published Date : Jan 01, 2011