Cybermedlife - Therapeutic Actions Balneotherapy


The influence of peloids from volcanic deposits in Azerbaijan on the dynamics of sugar content in blood and urine and the wound healing in patients at the early stages of diabetic gangrene of the lower extremities

Abstract Title: [The influence of peloids from volcanic deposits in Azerbaijan on the dynamics of sugar content in blood and urine and the wound healing in patients at the early stages of diabetic gangrene of the lower extremities]. Abstract Source: Vopr Kurortol Fizioter Lech Fiz Kult. 2009 Nov-Dec(6):42-3. PMID: 20050166 Abstract Author(s): M Ia Nasirov, F M Efendieva, D A Ismaĭlova Abstract: The treatment of diabetic patients with pyonecrotic lesions in the lower extremities requires prolonged reflexo-segmental balneophysiotherapy to normalize functions of the nerve centres. Curative volcanic mud solutions (15-24 g/l) enriched with organic and nonorganic biologically active compounds from volcanic deposits in Azerbaijan were used for the first time to treat such patients. Peloids were applied to the lumbar region (location of sympathetic nerve nodes) and the lower legs above and beneath the affected sites. The patients were subjected to 12-15 seances of peloidotherapy (at 40-41 degrees Celsius) each lasting 20-30 minutes. The treatment was preceded by wound sanation using the standard procedure and a course of antibiotic therapy based on individual antibiotocograms. A total of 86 daibetic patients with leg gangrene underwent rheovasographic thermovision examination that revealed enhanced blood supply to the affected extremities under the action of the applied peloids. Peloidotherapy resulted in the normalization of blood and urine glucose levels in 53 (63%) of the patients. Simultaneously, the doses of medicamentous therapy could be lowered. Wound and ulcer healing was completed in the majority of the patients (86%) by the end of balneophysiotherapy when fresh granulation tissue began to develop and signs of oedema to disappear. These patients no longer needed amputation. Article Published Date : Nov 01, 2009

Spa therapy in rheumatology. Indications based on the clinical guidelines of the French National Authority for health and the European League Against Rheumatism, and the results of 19 randomized clinical trials

Abstract Title: [Spa therapy in rheumatology. Indications based on the clinical guidelines of the French National Authority for health and the European League Against Rheumatism, and the results of 19 randomized clinical trials]. Abstract Source: Bull Acad Natl Med. 2009 Jun;193(6):1345-56; discussion 1356-8. PMID: 20120164 Abstract Author(s): Alain Françon, Romain Forestier Article Affiliation: Centre de recherches rhumatologiques et thermales, 73100 Aix les Bains. This email address is being protected from spambots. You need JavaScript enabled to view it. Abstract: The objective of this work was to update the rheumatologic indications of spa therapy, based on clinical practice guidelines published by the French National Authority for Health (HAS) and the European League Against Rheumatism (EULAR), and on the results of randomized clinical trials (RCT) METHODOLOGY: We first examined the indications for which spa therapy is mentioned and/or recommended in HAS and EULAR guidelines. We then identified RCTs in spa therapy and rheumatology by using the key words spa therapy, balneology, balneotherapy, hydrotherapy, mud therapy and mineral water in the Pubmed, Pascal and Embase databases. Only RCTs including a statistical analysis of between-group outcomes were retained We also examined the possible contribution of RCTs not listed in the bibliography of the guidelines. RESULTS: RECOMMENDATIONS: spa therapy is recommended by HAS for chronic lower back pain, rank B and for stabilized rheumatoid arthritis, rank C. In ankylosing spondylitis, EULAR classifies spa therapy along with physiotherapy, rank A. In fibromyalgia, EULAR recommends hot-water balneology, an important component of spa therapy, rank B, based on five RCTs, of which three were carried out in thermal springs. Nineteen RCTs that comprised a statistical comparison of between-group outcomes were identified Sixteen studies indicated a persistent improvement (at least twelve weeks) in pain, analgesic and non-steroidal antiinflammatory drug consumption, functional capacity and/or quality of life, in the following indications: chronic lower back pain, knee osteoarthritis, hand osteoarthritis, fibromyalgia, ankylosing spondylitis andrheumatoidarthritis (PR). CONCLUSION: Spa therapy, or hot-water balneology, appears to be indicated for chronic low back pain, stabilized rheumatoid arthritis, ankylosing spondylitis and fibromyalgia. RCT findings suggest that patients with knee and hand osteoarthritis might also benefit. Article Published Date : Jun 01, 2009

The effect of mild whole-body hyperthermia on systemic levels of TNF-alpha, IL-1beta, and IL-6 in patients with ankylosing spondylitis.

Abstract Title: The effect of mild whole-body hyperthermia on systemic levels of TNF-alpha, IL-1beta, and IL-6 in patients with ankylosing spondylitis. Abstract Source: Clin Rheumatol. 2009 Apr;28(4):397-402. Epub 2008 Dec 17. PMID: 19089489 Abstract Author(s): Ingo H Tarner, Ulf Müller-Ladner, Christine Uhlemann, Uwe Lange Abstract: Serial mild whole-body hyperthermia is a widely used balneotherapy modality for clinically inactive ankylosing spondylitis (AS) in rehabilitative medicine. Thus far, the mechanisms of its favorable influence on the symptoms of AS are not completely understood. We therefore analyzed the effect of mild whole-body hyperthermia on the systemic levels of pivotal proinflammatory cytokines. Twelve male subjects with AS and 12 healthy control subjects received nine cycles of whole-body hyperthermia (target body core temperature, 38.5 degrees C; duration, 50 min). Serum samples were taken at the beginning of the last cycle and at 1, 6, and 24 h for measurement of tumor necrosis factor alpha, interleukin 1beta and interleukin 6. Significant differences of cytokine levels were found between both groups. In AS patients, hyperthermia caused a significant reduction of all cytokines by 40-50%. Thus, serial mild whole-body hyperthermia in AS results in heat-induced changes of the proinflammatory cytokine network. Article Published Date : Apr 01, 2009

Synchronous balneophototherapy is effective for the different clinical types of psoriasis.

Abstract Title: Synchronous balneophototherapy is effective for the different clinical types of psoriasis. Abstract Source: Neurochem Res. 2007 Dec;32(12):2094-102. Epub 2007 Jul 7. PMID: 16164712 Abstract Author(s): P Holló, R Gonzalez, M Kása, A Horváth Article Affiliation: Department of Dermatovenereology and Dermatooncology Semmelweis Medical School, Budapest, Hungary. This email address is being protected from spambots. You need JavaScript enabled to view it. Abstract: BACKGROUND: The efficacy of synchronous balneophototherapy in clearing psoriasis is based on the multiple-targeted effects of UVB light and Dead Sea salt. Their synchronous application produces a synergic effect. OBJECTIVE: The purpose of this retrospective study is: 1) to evaluate the efficacy of synchronous balneophototherapy for treating different clinical types of psoriasis; 2) to determine whether there is any difference between response to treatment, and 3) to gain more data in order to predict the effect of treatment in different clinical types, and thus to support the selection of patients for treatment. METHODS: Patients received a basic course of synchronous balneophototherapy according to the Regensburg scheme, consisting of 35 treatment sessions, followed by a maintenance course of a further 25 treatments. The patients' skin status was monitored by weekly assessment using the PASI score throughout the course. The efficacy of the treatment was evaluated through the results of 373 patients treated according to protocol during the basic course, and the results of 78 of these patients during the maintenance course. One hundred and eighty-six patients were enrolled into the study comparing the efficacy of the basic course for the different clinical types of psoriasis: data of patients with large plaques, small plaques, guttate and confluating type of skin signs were summarized and compared. RESULTS: During the basic course of treatment 70.7% improvement of the average PASI index was observed; the average PASI index decreased from 16.14 to 4.73. A further improvement from 4.58 to 4.27 of the average PASI was found during the maintenance therapy. Small plaque-type skin signs showed the best response with a PASI decrease of 76.1%; Guttate type had a PASI decrease of 73.7%, large plaque type, 67.1% and confluating type, 62%. Comparing data with the average PASI decrease, a statistically significant lower decrease was found in confluating type cases. CONCLUSIONS: These results confirm that synchronous balneophototherapy is an effective treatment modality for different clinical types of psoriasis. Patients with small plaques have the greatest chance of the most marked clinical clearing; guttate and large plaque types of psoriasis also respond well to the treatment. Article Published Date : Dec 01, 2007

The efficacy of balneotherapy and mud-pack therapy in patients with knee osteoarthritis.

Abstract Title: The efficacy of balneotherapy and mud-pack therapy in patients with knee osteoarthritis. Abstract Source: Joint Bone Spine. 2007 Jan;74(1):60-5. Epub 2006 Nov 29. PMID: 17223602 Abstract Author(s): Deniz Evcik, Vural Kavuncu, Abdurrahman Yeter, Ilknur Yigit Abstract: OBJECTIVES: Knee osteoarthritis (OA) is a common chronic degenerative disorder. There are various treatment modalities. This study was planned to investigate the efficacy of balneotherapy, mud-pack therapy in patients with knee OA. METHODS: A total of 80 patients with knee OA were included. Their ages ranged between 39-78. The patients were separated in to three groups. Group I (n=25) received balneotherapy, group II (n=29) received mud-pack therapy and group III (n=26) was hot-pack therapy group. The therapies were applied for 20 min duration, once a day, five times per week and a total of 10 session. Patients were assessed according to pain, functional capacity and quality of life parameters. Pain was assessed by using Visual Analogue Scale (VAS) and Western Ontario McMaster Osteoarthritis Index (WOMAC) pain scale (0-4 likert scale). Functional capacity was assessed by using WOMAC functional capacity and WOMAC global index. Quality of life was evaluated by Nottingham Health Profile (NHP) self-administered questionnaire. Also physician's global assessment and the maximum distance that patient can walk without pain, were evaluated. The assessment parameters were evaluated before and after three months. RESULTS: There were statistically significant improvement in VAS and WOMAC pain scores in group I (p<0.001), group II and III (p<0.05). The WOMAC functional and global index also decreased in group I (p<0.05), group II (p<0.001) and hot-pack group (p<0.05). Quality of life results were significantly improved in balneotherapy and mud-pack therapy groups (p<0.05). No difference was observed in hot-pack therapy group (p>0.05). The maximum distance was improved both in group I and II (p<0.05) but not in group III. Also physician's global assessment was found to be improved in all groups (p<0.05). CONCLUSIONS: Balneotherapy and mud-pack therapy were effective in treating patients with knee OA. Article Published Date : Jan 01, 2007
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[The comprehensive approach to the rehabilitative treatment of junior athletes].

Related Articles [The comprehensive approach to the rehabilitative treatment of junior athletes]. Vopr Kurortol Fizioter Lech Fiz Kult. 2017;94(1):46-50 Authors: Stepanenko NP, Levitskaya TE, Tsekhmeistruk EA, Tren'kaeva NA, Tyulyupo SV, Dostovalova OV, Kremeno SV, Shakhova SS, Chekcheeva VD Abstract AIM: The objective of the present study was the development of the comprehensive program for the medico-psychological follow-up of the male and female junior athletes (rhythmic gymnastics) with the purpose of stabilizing their hormonal and emotional status, as well as improving sport performances based on the use of modern hardware-software technologies. MATERIAL AND METHODS: The comprehensive examination of 72 female athletes at the mean age of 11.5±0.6 years attending R. Kuznetsov specialized school of rhythmic gymnastics of the Olympic reserve in the city of Seversk has been undertaken on the basis of Tomsk Research Institute of Balneology and Physiotherapy, the branch of Siberian Federal Research and Clinical Centre. RESULTS: The program of comprehensive medical psychological rehabilitation for the junior athletes of either sex engaged in sportive activities requiring precise technical actions has been elaborated. The method of the combined therapeutic treatment included physical exercises therapy, manual massage, dry carbonic bathtubs, psychological activities with the application of biological feedback trainings and cognitive trainings; it was intended for the correction of the hormonal status and the improvement of the psycho-emotional conditions of the athletes. The combined treatment based on the use of the modern hardware-software technologies was shown to promote the restoration and development of the psychophysical and psychological qualities of the male and female junior athletes indispensable for the maintenance of their high readiness for the efficient sports activities at the subsequent stages of the training cycle. In addition, such treatment enhances the adaptation resources of the athletes. PMID: 28374732 [PubMed - in process]

Case of Legionnaires disease in a neonate following a home birth in a heated birthing pool, England, June 2014.

Related Articles Case of Legionnaires disease in a neonate following a home birth in a heated birthing pool, England, June 2014. Euro Surveill. 2014 Jul 24;19(29): Authors: Phin N, Cresswell T, Parry-Ford F, Incident Control Team Abstract Public Health England was notified of Legionnaires' disease in a neonate following a home birth in a heated birthing pool filled from the domestic hot water supply two weeks earlier. We describe the incident, sampling results, and public health actions. It is recommended that heated birthing pools should not be used for home births. Neonates developing pneumonia within 14 days of labour or birth in any birthing pool should be tested for Legionnaires' disease. PMID: 25080139 [PubMed - indexed for MEDLINE]

[Mineral springs on the north-east of Caucasus and its role in the treatment of soldiers of the Russian army in XIX--beginning XX c].

Related Articles [Mineral springs on the north-east of Caucasus and its role in the treatment of soldiers of the Russian army in XIX--beginning XX c]. Voen Med Zh. 2013 Jul;334(7):62-6 Authors: Akhmadov TZ, Poddubnyĭ MV Abstract The article is concerned to the history of formation of sanitary-treatment stations on the North Caucasus, in Chechnya (Goryachevodsky and Mikhailovsky mineral springs) till 1917 year. The basis of the article are archive documents, scientific papers of contemporaries and official documents. Goryachevodsky and Mikhailovsky mineral springs were more than 70 years the one the best recreative base of the Caucasian standing army including the caucasian cossack troop. The sanitary-treatment stations were of great importance during the active military actions with Hill people within the territory of Chechnya and Dagestan, during the Crimean War (1853-1856), The Russo-Turkish War of 1877-1878 and the First World War (1914-1918), when the amount of the wounded and ill soldiers increased. PMID: 24341013 [PubMed - indexed for MEDLINE]

Inflammatory arthritis. The role of physical and rehabilitation medicine physicians. The European perspective based on the best evidence. A paper by the UEMS-PRM Section Professional Practice Committee.

Related Articles Inflammatory arthritis. The role of physical and rehabilitation medicine physicians. The European perspective based on the best evidence. A paper by the UEMS-PRM Section Professional Practice Committee. Eur J Phys Rehabil Med. 2013 Aug;49(4):551-64 Authors: Küçükdeveci AA, Oral A, Ilıeva EM, Varela E, Valero R, Berteanu M, Chrıstodoulou N Abstract One of the objectives of the Professional Practice Committee (PPC) of the Physical and Rehabilitation Medicine (PRM) Section of the Union of European Medical Specialists (UEMS) is the development of the field of competence of PRM physicians in Europe. To achieve this objective, UEMS PRM Section PPC has adopted a systematic action plan of preparing a series of papers describing the role of PRM physicians in a number of disabling health conditions, based on the evidence of effectiveness of the physical and rehabilitation medicine interventions. Inflammatory arthritis is a major cause of disability with an important economic burden in society. The goals in the management of inflammatory arthritis are to control pain and disease activity, prevent joint damage, protect and enhance function and improve quality of life. This paper aims to define the role of PRM physicians in people with inflammatory arthritis. PRM interventions imply non-pharmacological treatments which include patient education for joint protection, energy conservation and self-management techniques, exercise therapy, physical modalities, orthoses/assistive devices and balneotherapy. Therapeutic patient education and exercises are the cornerstones of therapy with strong evidence of their effectiveness to improve function. Physical modalities are primarily used to decrease pain and stiffness whereas orthoses/assistive devices are usually prescribed to enhance activities and participation. PRM physicians have distinct roles in the management of people with inflammatory arthritis such that they effectively organise and supervise the PRM program in the context of interdisciplinary team work. Their role starts with a comprehensive assessment of patient's functioning based on the International Classification of Functioning Disability and Health (ICF) as the framework. In the light of this assessment, appropriate PRM interventions individualised for the patient are administered. Future research and actions regarding the role of PRM in inflammatory arthritis should target access to care, updates on the use and effectiveness of physical modalities, orthoses/assistive devices, and standardization of therapeutic patient education programs. PMID: 24084414 [PubMed - indexed for MEDLINE]

Non-invasive measurement of carbon monoxide burden in Guatemalan children and adults following wood-fired temazcal (sauna-bath) use.

Related Articles Non-invasive measurement of carbon monoxide burden in Guatemalan children and adults following wood-fired temazcal (sauna-bath) use. J Environ Monit. 2011 Aug;13(8):2172-81 Authors: Lam N, Nicas M, Ruiz-Mercado I, Thompson LM, Romero C, Smith KR Abstract The use of wood-fired steam baths, or temazcales, is a potentially dangerous source of CO exposure in Guatemalan Highland communities where adults and children use them regularly for bathing, relaxation, and healing purposes. Physical characteristics of children predispose them to absorb CO faster than adults, placing them at greater exposure and health risks. Efforts to quantify temazcal exposures across all age groups, however, have been hampered by the limitations in exposure measurement methods. In this pilot study we measured COHb levels in children and adults following use of the temazcal using three field-based, non-invasive CO measurement methods: CO-oximetry, exhaled breath, and by estimation of COHb using micro-environmental concentrations and time diaries. We then performed a brief comparison of methods. Average CO concentrations measured during temazcal use were 661 ± 503 ppm, approximately 10 times the 15 min WHO guideline. Average COHb levels for all participants ranged from 12-14% (max of 30%, min 2%), depending on the method. COHb levels measured in children were not significantly different from adults despite the fact that they spent 66% less time exposed. COHb measured by CO-oximetry and exhaled breath had good agreement, but precision of the former was affected substantially by random instrument error. The version of the field CO-oximeter device used in this pilot could be useful in screening for acute CO exposure events in children but may lack the precision for monitoring the burden from less extreme, but more day-to-day CO exposures (e.g. indoor solid fuel use). In urban settings, health effects in children and adults have been associated with chronic exposure to ambient CO concentrations much lower than measured in this study. Future research should focus on reducing exposure from temazcales through culturally appropriate modifications to their design and practices, and targeted efforts to educate communities on the health risks they pose and actions they can take to reduce this risk. PMID: 21687856 [PubMed - indexed for MEDLINE]

[Crenobalneotherapy: a medical and scientific update].

Related Articles [Crenobalneotherapy: a medical and scientific update]. Bull Acad Natl Med. 2009 May;193(5):1165-80 Authors: Roques CF, de Boissezon X, Queneau P Abstract The PubMed database contains about eighty scientific papers on crenobalneotherapy (i.e., medical balneology or spa therapy) published in the last three years, mostly in journals with an impact factor. These studies focus on the actions of thermomineral products (waters, muds, gases, steam) on biological systems (immune system, antioxidant system, cytokine networks, nociception, etc.). Hot mineral waters can have an action on the circulatory system. Ingested mineral water can act on carbohydrate, lipid and mineral metabolism. Dermocosmetologic mineral products have shown real benefits. Medical benefits of thermal treatment have been observed in patients with rheumatic conditions, psoriasis, venous insufficiency, ENT conditions, gynecolgical disorders, and anxiety. Unfortunately, many publications in this area suffer from methodological flaws. Clinical investigations of thermal medicine encounter dificulties of a methodological and financial nature, and problems of patient recruitment. The aim of the French thermal research institute is to provide support and advice for teams wishing to conduct well-designed controlled trials. PMID: 20120394 [PubMed - indexed for MEDLINE]

[The role of natural medicinal factors in federal and regional recreational zones in the rehabilitation of patients following surgical treatment of pathological periapical tissues and oral cavity phlegmonas].

Related Articles [The role of natural medicinal factors in federal and regional recreational zones in the rehabilitation of patients following surgical treatment of pathological periapical tissues and oral cavity phlegmonas]. Vopr Kurortol Fizioter Lech Fiz Kult. 2009 Nov-Dec;(6):40-1 Authors: Abstract The necessity of considering the problem with which this paper is concerned arises from the current scientific discussion of the actions of physicians working in municipal healthcare facilities and sanatoria directed toward rehabilitation of patients after surgical treatment of periapical tissues and oral cavity phlegmonas. The study elucidated the mechanism of action of mineral waters (alkaline, sodium hydrocarbonate or boron-containing water with elevated fluorine and chlorine content) extracted from natural deposits of the Belgorod Region and Krasnodar Krai (Territory). It was shown that drinking these waters contributed to the correction of the disturbed balance in the ratio of sodium and potassium ions excreted with urine and to the positive dynamics of serum phosphorus level in the patients included in this study. PMID: 20050165 [PubMed - indexed for MEDLINE]

Hot air sauna burns--review of their etiology and treatment.

Related Articles Hot air sauna burns--review of their etiology and treatment. J Burn Care Res. 2009 Jul-Aug;30(4):705-10 Authors: Koljonen V Abstract Hot air sauna burns (HASBs) are rare but potentially fatal injuries with simultaneous rhabdomyolysis. The mechanism of HASBs involves prolonged exposure to hot air because of immobility. The burned areas are on the parts of the body that are directly exposed to hot air. This type of heat exposure results in a complex injury, in which full-thickness skin damage occurs concurrently with deeper tissue destruction. Sauna bathing is becoming more and more a popular recreational activity around the world. The objective of this review article is to familiarize burn care specialists on this unique and clinically challenging type of burn injury and to illustrate our department's long experience in treating patients with HASBs. A thorough review of the current literature with PubMed interface using the key word "hot air sauna burn" was performed. Six articles were found under this topic, with 42 patients being recorded. Therapy for rhabdomyolysis and aggressive early operative treatment are the cornerstones of hot air sauna burn treatment and lifesaving actions. Treatment of HASBs differs from the more common flame and scald burns. Hot air sauna burn patients require early and aggressive surgical intervention to treat the rhabdomyolysis. Amputations and excision of the affected muscles are common. Contrary to other types of burn injuries, these patients need flap coverage during the acute surgery phase. Microvascular free flaps usually perish because of damage of vascular structures deeper to the visible burned cutaneous areas. Pedicled flaps are the treatment of choice. PMID: 19506509 [PubMed - indexed for MEDLINE]

Immersion in CO2-rich water containing NaCl diminishes blood pressure fluctuation in anesthetized rats.

Related Articles Immersion in CO2-rich water containing NaCl diminishes blood pressure fluctuation in anesthetized rats. Int J Biometeorol. 2007 Dec;52(2):109-16 Authors: Yamamoto N, Hashimoto M Abstract Remarkably, bathing in hot springs containing high concentrations of carbon dioxide (CO(2)) influences cardiovascular function more than bathing in fresh water. The CO(2)-enriched water in hot springs generally contains many salts, whose interactions remain unknown. We separately evaluated the actions of individual factors in CO(2)-enriched water and confirmed that CO(2) and NaCl have combined effects on blood pressure fluctuations in anesthetized rats. Animals equipped with sensor probes to monitor body temperature, skin blood flow and arterial blood pressure were immersed in bathwater (35 degrees C) containing CO(2) with NaCl, KCl or sucrose. The effects of these factors on cardiovascular function were evaluated using power-spectral analysis of fluctuations in blood pressure and heart rate. Compared with immersion in tap water, heart rate and skin vascular resistance were reduced during immersion in CO(2)-enriched water irrespective of the presence of other components. In terms of the very low frequency range (0.02-0.195 Hz), the power of blood pressure fluctuation during immersion was significantly reduced when the CO(2)-enriched water contained more than 1.5% NaCl but was not influenced by other components of similar osmotic pressure and the same specific gravity. The results indicated that the coexistence of CO(2) and sodium ions in bathwater reduce blood pressure fluctuations, and suggested that this combination effect of CO(2) and salt contributes to the sedative effect on human cardiovascular functions while bathing in CO(2)-hot springs. PMID: 17569993 [PubMed - indexed for MEDLINE]

[Magnesium-containing mineral waters in the treatment of patients with cardial manifestations of gastroesophageal reflux disease].

Related Articles [Magnesium-containing mineral waters in the treatment of patients with cardial manifestations of gastroesophageal reflux disease]. Vopr Kurortol Fizioter Lech Fiz Kult. 2006 Nov-Dec;(6):31-4 Authors: Efendieva MT, Batdieva VA, Rusenko NI Abstract Drinking of sulphate-magnesium-calcium water by patients with gastroesophageal reflux disease of the first degree with cardial manifestations has a prokinetic and anti-inflammatory action leading to attenuation of gastroesophageal reflux and positive cardiovascular changes. Marked therapeutic efficacy of the water is due to specific action of magnesium ions having membrane-stabilizing, sedative effects, pronounced prokinetic and sympatholytic actions which manifest with weakening of ergotropic actions, higher efficacy of cardiac activity. These convert to a noticeable clinical response--regress of clinical symptoms and potentiation of anti-arrhythmic effects. PMID: 17201221 [PubMed - indexed for MEDLINE]

Comano's (Trentino) thermal water interferes with the expression and secretion of vascular endothelial growth factor-A protein isoforms by cultured human psoriatic keratinocytes: a potential mechanism of its anti-psoriatic action.

Related Articles Comano's (Trentino) thermal water interferes with the expression and secretion of vascular endothelial growth factor-A protein isoforms by cultured human psoriatic keratinocytes: a potential mechanism of its anti-psoriatic action. Int J Mol Med. 2006 Jul;18(1):17-25 Authors: Chiarini A, Dal Pra I, Pacchiana R, Menapace L, Zumiani G, Zanoni M, Armato U Abstract Thermal balneotherapy with Comano spa's water (CW; Trentino, Italy) is used for psoriasis and other skin disorders but the mechanism(s) of action of this hypotonic water are unknown. Since skin psoriatic manifestations are thought to be angiogenesis-dependent, we assessed CW's effects on the expression and release of VEGF-A protein isoforms by cultured human lesional keratinocytes isolated from skin biopsies performed in 9 patients. Confluent, psoriatic keratinocytes were exposed for 11 days to DMEM, whose chemicals had been dissolved in either deionised water (DW-DMEM, controls) or CW (CW-DMEM, treated cells). As detected by Western immunoblotting (WB), incubation in CW-DMEM elicited, with respect to DW-DMEM, an increase in intracellular and/or cell-bound L-VEGF-A189 and L-VEGF-A165 48 kDa protein isoforms with no concurrent change in L-VEGF-A121 and L-VEGF-A165 45 kDa proteins. Moreover, WB analysis of the secreted VEGF-A (sVEGF-A) proteins showed that the 20 and 15 kDa bands corresponding to different VEGF-A isoforms were directly and remarkably reduced in keratinocyte-conditioned CW-DMEM vs. DW-DMEM. Thus, CW interferes with VEGF-A isoform expression and secretion by the psoriatic keratinocytes. These effects would reduce all VEGF-A-mediated angiogenic, vessel permeabilising, and chemotactic effects, thereby at least in part explaining the beneficial actions of CW balneotherapy on the clinical manifestations of psoriasis. PMID: 16786151 [PubMed - indexed for MEDLINE]

Towards understanding the unpresentable in nursing: some nursing philosophical considerations.

Related Articles Towards understanding the unpresentable in nursing: some nursing philosophical considerations. Nurs Philos. 2006 Jan;7(1):23-35 Authors: Cameron BL Abstract While nursing practice embodies certain observable and sometimes habitual actions, much inheres in these actions that is not immediately discernible. Taking on Lyotard's exegesis of the unpresentable, I undertake an analysis of the unpresentable as it occurs in nursing practices. The unpresentable is a place of alterity often excluded from dominant discourses. Yet this very alterity is what practising nurses face day after day. Drawing from two nursing situations, one from a hermeneutic phenomenological study and the other from the literature, I elucidate the unpresentable from a nursing point of view. Evoking Lyotard as well as selected philosophers from the continental philosophical tradition, I also question whether nursing in its present discourse is capable of responding to the unpresentable in nursing situations. Through the philosophical stance of presentation and representation, I delineate the urgent need to bring the otherness of the unpresentable into our nursing discourse. Nurses in practice confront a wide array of human differences and diversities and come to the realization that no framework alone can ever really have primacy over the multiform presentations of human suffering that so strikingly evoke alterity. PMID: 16412200 [PubMed - indexed for MEDLINE]

[Experimental base for use of low-mineral water with a high concentration of organic substances in balneological practice].

Related Articles [Experimental base for use of low-mineral water with a high concentration of organic substances in balneological practice]. Vopr Kurortol Fizioter Lech Fiz Kult. 2005 Sep-Oct;(5):8-11 Authors: Martyniuk VK, Fedorov AA, Kurochkin VIu, Volkova NA, Okunev PV, Zhernakova ZM, Chudinova OA, Roslyĭ OF, Guliaev VIu, Potapov LV Abstract Experimental evidence on stability of chemical composition (1991-2004), toxic and skin-irritating, mitotic and mutagenic, bacterio- and fungostatic actions of low-mineral water "Salekhard" with a high concentration of organic substances justifies initiation of clinical trials of therapeutic effects of this novel balneological factor in different diseases (locomotor, nervous, cardiovascular, cutaneous, etc.). PMID: 16317998 [PubMed - indexed for MEDLINE]

[Combined use of hydrogen sulfide baths and galvanopeloid therapy with magnetolaser radiation in osteoarthrosis patients at a health resort].

Related Articles [Combined use of hydrogen sulfide baths and galvanopeloid therapy with magnetolaser radiation in osteoarthrosis patients at a health resort]. Vopr Kurortol Fizioter Lech Fiz Kult. 2005 Jul-Aug;(4):23-5 Authors: Ibadova GD, Mamishev SN, Zavora MI, Sarian LA Abstract The study included 174 patients with osteoarthrosis (OA) of the first and second x-ray stage, subclinical or mild reactive synovitis. The patients received sanatorium treatment including hydrogen sulphide balneotherapy, galvanopeloid therapy with sulphide muds of Imeretinsk deposit (Sochi) by the segmental-local technique, prior magnetic laser radiation in some cases. Anesthetic, anti-inflammatory effects were found which proved highest in consecutive use of magnetolaser radiation and galvanopeloid therapy as shown by normalization of autonomic function, improvement of peripheral circulation, inhibition of proteolysis due to antioxidant and adaptogenic actions. PMID: 16149413 [PubMed - indexed for MEDLINE]

[Current evaluation of efficacy of radon baths of various concentrations during rehabilitation of patients with seronegative spondylarthritis].

Related Articles [Current evaluation of efficacy of radon baths of various concentrations during rehabilitation of patients with seronegative spondylarthritis]. Vopr Kurortol Fizioter Lech Fiz Kult. 2005 Jul-Aug;(4):13-7 Authors: Barnatskiĭ VV, Grigor'eva VD, Kaliushina EN Abstract 141 patients with seronegative spondylarthritis including ankylosing spondylarthritis (n = 90), reactive arthritis and Reiter's disease (n = 51) took water radon baths (concentration 1.5, 3.0 and 4.5 kB/l). The baths proved similarly effective in patients with seronegative spondylarthritis. They produced analgetic, anti-inflammatory actions, raised quality of life for such patients. PMID: 16149410 [PubMed - indexed for MEDLINE]

[Vibrophoresis of mud lipid extract in the rehabilitation of patients with osteoarthrosis].

Related Articles [Vibrophoresis of mud lipid extract in the rehabilitation of patients with osteoarthrosis]. Vopr Kurortol Fizioter Lech Fiz Kult. 2004 Jan-Feb;(1):30-3 Authors: Reshetova GG, Zaripova TN, Novikova SV, Titskaia EV, Matis EIa Abstract Experimental and clinical evidence (76 patients with osteoarthrosis) justifies combined use of thermovibration massage and lipid extract from therapeutic mud eplir. This combination produces analgetic, antiedematic, antiinflammatory actions and promotes normalization of systemic immunity and peripheral hemodynamics. PMID: 15052844 [PubMed - indexed for MEDLINE]

Comparative study of the thermal properties of mud and peat solutions applied in clinical practice.

Related Articles Comparative study of the thermal properties of mud and peat solutions applied in clinical practice. Biomed Tech (Berl). 2003 Nov;48(11):301-5 Authors: Beer AM, Grozeva A, Sagorchev P, Lukanov J Abstract Different peloids as e.g. mud and peat have been traditionally used for therapeutic purposes successfully, especially of there thermal actions. It was the aim of the experimental study to compare the thermal properties of two peloids, mud and peat, with a view to assessing their thermal effects when they are applied in clinical practice. The studies were carried out using peat of the marsh type of peats (Hochmoor), and curative Pomorie (Bulgaria) mud. As important parameters were determined the specific thermal capacity at constant pressure (Cp), the density of solutions (rho), the cooling rate (m), the coefficient of temperature transfer (a) of solutions and the coefficient of thermal conductivity (lambda) of solutions of peat and curative mud, compared to water bath. The comparative studies of the thermal properties of water and water solutions of peat and curative mud show that the thermal effect of the water bath is substantially smaller than that of the peat and mud applications. This difference is due to a greater extent to the high values of the dynamic viscosity, not allowing cooling by convection and protecting the surface of the skin upon applications of peloid solutions with a higher temperature. PMID: 14661533 [PubMed - indexed for MEDLINE]

Nursing management of fever in children: a systematic review.

Related Articles Nursing management of fever in children: a systematic review. Int J Nurs Pract. 2003 Feb;9(1):S1-8 Authors: Watts R, Robertson J, Thomas G Abstract OBJECTIVES: The aim of the present review was to determine whether the best available evidence supports the types and timing of the various nursing interventions that are commonly used to reduce fever in non-critically-ill children, and to what extent the outcomes are influenced by these nursing actions. METHODS: Studies included were randomised or quasi-randomised controlled trials that involved non-critically-ill children with a fever aged between 3 months and 16 years. The search strategy sought to identify both published and unpublished research reports in the English language and covered all major databases up to 1998. The methodological quality of each study was assessed by two independent reviewers using a piloted critical appraisal checklist. Despite all studies being randomised, heterogeneity precluded conduction of a meta-analysis; therefore, evidence was synthesised using narrative summaries. RESULTS: Ten studies were assessed as being of sufficient quality to be included in the review. These studies addressed two of the intervention categories identified in the protocol: (i) administration of antipyretics (paracetamol); and (ii) direct cooling measures on the outcome measure (reduction of or prevention of increase in fever). The review found little benefit from sponging in temperate climates and usually at the expense of the child's comfort. There may be situations in high environmental temperatures and high humidity, or where there is a need for immediate temperature reduction, in which sponging may be warranted. Risks were identified when paracetamol was administered on a sustained basis over even a short period of time and above a relatively low total daily dosage. There was a lack of evidence to support the administration of antipyretics to reduce the incidence of febrile convulsions. There is a need for parental education that focuses on knowledge of the body's protective physiological responses and how to support these responses. CONCLUSION: The primary purpose for intervening when a child has a fever is to increase the child's comfort. This consideration should be weighed against any harm that might result from intervening. There was a lack of evidence to support the routine use of sponging. The administration of paracetamol should be used selectively and with caution. In summary, care needs to be individualised, based on current knowledge of the effectiveness and risks of interventions. PMID: 12588622 [PubMed - indexed for MEDLINE]

[Mechanism of the effect of aqueous peat extract on spontaneous contractile activity of smooth muscles].

Related Articles [Mechanism of the effect of aqueous peat extract on spontaneous contractile activity of smooth muscles]. Forsch Komplementarmed Klass Naturheilkd. 2000 Oct;7(5):237-41 Authors: Beer AM, Lukanov J, Sagorchev P Abstract BACKGROUND: There are reports in the literature about the effects of peat and its products on spontaneous contractile activity (SCA) of smooth muscles. In our earlier work we showed that the aqueous peat extract is a stimulus for SCA of smooth muscle fibres. After longstanding (4-5 h) influence from aqueous peat extract, a self-blocking effect of these influences can be observed. The mechanism of action could not be determined up to now. PURPOSE: The purpose of this study is to elucidate the peat mechanism of action. MATERIAL AND METHODS: In organ baths, the effects of aqueous peat extract on the SCA from smooth muscles have been studied under normal conditions and with presence of different receptor blocking substances. RESULTS: Our investigations show that only with simultaneous blocking of alpha(2) and D(2) receptors the stimulating activity of aqueous peat extract on the SCA of smooth muscle fibres can be suppressed. The self-blocking actions of the stimulating activity of aqueous peat extract on the SCA of smooth muscles are interconnected with blocking of alpha(2 ) adreno and D(2) receptors. CONCLUSION: The aqueous peat extract contains biologically active substances, which have a partial agonistic effect on alpha(2 ) and D(2) dopamine receptors. Corresponding to the results we start out at pharmacological effects as they are known from the mentioned receptors. The clinical efficacy have to be shown by clinical trials. PMID: 11096263 [PubMed - indexed for MEDLINE]

[Spa therapy and sadness].

Related Articles [Spa therapy and sadness]. An R Acad Nac Med (Madr). 1999;116(2):279-95; discussion 295-6 Authors: Armijo Valenzuela M Abstract The feeling of sadness is said to be an individual problem which can take advantage of an adequate Spa therapy in all its complexity. The sadness as a feeling of disproportional affective reaction with mental consequences, can find relief in the Spa cures and their different structural elements like the hydrothermal techniques, psychical actions, environmental features..., etc. These Spa cures have many favourable effects not only on the body but also on the mind, being capable of liberating the mind of worries and respecting the peculiar personality and way of suffering of the patient. PMID: 10682393 [PubMed - indexed for MEDLINE]
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