×

Message

EU e-Privacy Directive

This website uses cookies to manage authentication, navigation, and other functions. By using our website, you agree that we can place these types of cookies on your device.

View e-Privacy Directive Documents

You have declined cookies. This decision can be reversed.

Dietary Modification - Low Carbohydrate-Ketogenic

Ketogenic diet and childhood neurological disorders other than epilepsy: an overview.

Written by CYBERMED LIFE NEWS
Abstract Title:

Ketogenic diet and childhood neurological disorders other than epilepsy: an overview.

Abstract Source:

Expert Rev Neurother. 2016 Nov 21:1-13. Epub 2016 Nov 21. PMID: 27841033

Abstract Author(s):

Alberto Verrotti, Giulia Iapadre, Simone Pisano, Giangennaro Coppola

Article Affiliation:

Alberto Verrotti

Abstract:

In the last years, ketogenic diet (KD) has been experimentally utilized in various childhood neurologic disorders such as mitochondriopathies, alternating hemiplegia of childhood (AHC), brain tumors, migraine, and autism spectrum disorder (ASD). The aim of this review is to analyze how KD can target these different medical conditions, highlighting possible mechanisms involved. Areas covered: We have conducted an analysis on literature concerning KD use in mitochondriopathies, AHC, brain tumors, migraine, and ASD. Expert commentary: The role of KD in reducing seizure activity in some mitochondriopathies and its efficacy in pyruvate dehydrogenase deficiency is known. Recently, few cases suggest the potentiality of KD in decreasing paroxysmal activity in children affected by AHC. A few data support its potential use as co-adjuvant and alternative therapeutic option for brain cancer, while any beneficial effect of KD on migraine remains unclear. KD could improve cognitive and social skills in a subset of children with ASD.